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Low-field NMR VS High-field NMR: Same root and same source

The NMR family is huge and complex, including NMR spectroscopy, resonancia magnética, and relaxation NMR. Frequently heard are NMR spectroscopy, human body MRI, RMN de campo bajo, electron paramagnetic resonance, variable field NMR, and so on. Among the many nuclear magnetic brothers, NMR spectroscopy and human MRI are undoubtedly thebig brotherof the nuclear magnetic family.

Whether it is a low field or a high field, everyone has the same roots, the same family, the same family, like the twin brothers, the same genes, but different interests and expertise, life trajectory is also very different.

Analizador de RMN
From top to bottom, from left to right: NMR spectroscopy, human MRI, low field MRI, variable field MRI

For a long time, high-field spectroscopy NMR has a high position in the field of structural analysis because of its high sensitivity and resolution. Human body MRI has been favored for its contribution to tumor diagnosis because of its high resolution.

According to statistics from relevant departments, the annual cost of purchasing human magnetic resonance in domestic hospitals alone has exceeded 10 billion yuan, which is not a huge and expensive spectrum nuclear magnetic, and the scientific research cost of low-field nuclear magnetic does not exceed 100 million.

As brothers of the same root, low-field nuclear magnetic field survives under the aura ofbrothers”, like you have a brother or sister who is better than you in every aspect, so in this contrast and contrast, the low field The path of nuclear magnetic science is very difficult.

Both the high field and the low field are powerful assistants for scientific research. Just like we always like to compare our children with others, we can’t fall behind when other children go to cram school. Seeing other children sometimes have a few English words, hurry back home Take out Oxford and Cambridge English to arrange for the children.

Although the low-field nuclear magnetic field does not have such a high field strength, it is therefore possible to choose a permanent magnet, a material with stable magnetic field, no maintenance, small volume, no liquid nitrogen and liquid helium cooling, no shielded room, small footprint, high and low floors installation. It is such aleather” y “resistance”, so it is particularly lovely in terms of price, ease of operation, maintenance and so on.

Although low-field nuclear magnetics cannot perform structural analysis, they are more than capable of studying the phase motility of molecules. Moisture phase analysis, pore structure characterization, methane occurrence state characterization, and monitoring of the synthesis and decomposition of combustible ice are all indispensable.

MRI is thedominant geneof the nuclear magnetic family, and this low-field nuclear magnetic field is also perfectly inherited. The characterization of the internal cracks in the rock, the dynamic changes ofyou enter and retreatduring the two-phase displacement process, dynamic tracking studies of contrast in vivo in mice, and visual characterization of mouse fat distribution and tumors are all hard-core skills.

RMN en el dominio del tiempo
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If you want to give a reason for you to choose low-field nuclear magnetic, aside from the easy-to-operate, maintenance-free external features, then this reason must be: rich data form. To put it bluntly: Rich data can greatly improve the cost performance of the instrument.

The data forms provided by low-field nuclear magnetic fields that people often contact include: relaxation and MRI, the former provides quantitative data, the latter provides intuitive qualitative analysis, in fact, there should be four forms, and the other two include signal amplitude And multi-dimensional NMR technology. In addition to the high requirements of multi-dimensional NMR on instrument hardware and sequence, most of Niumag’s products can provide the first three data forms.

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