Body Fat Content Measurement by NIUMAG NMR

Body Fat Content Measurement by NIUMAG NMR

Body Fat Content Measurement

Nowadays, Obesity has become a public health problem that endangers human health globally. Obese people are more likely to have high blood pressure, diabetes, fatty liver than normal people, and severe obesity can even lead to respiratory depression. Obesity is also an important factor in causing non-alcoholic fatty liver disease. Non-alcoholic fatty liver disease (NAFLD) is a common liver disease with a prevalence of about 25%-40%.

Therefore, losing weight has become a problem that all human beings must face. Studying weight loss has become an important task for today’s biological researchers.

Often, rats are used as experimental subjects to test various types of fat-reducing drugs. Rats body composition measurement done by NMR imaging is the most helpful.

Body Fat Content on Rats model

The traditional rats body composition study of intrahepatic fat content can use chemical analysis, which is a standard measure of rats body composition. There is also bioelectrical impedance method (BIA), dual energy X-ray absorption spectrometry (DEXA), etc. These methods have shortcomings such as large error in measurement results, small scope of application, and easy influence. This application notes introduces the rats body composition analysis technology based on low-field NMR technology, which is very suitable for the study of liver fat content in rats models.

In addition to the rats model study of intrahepatic fat content, rats body composition analysis technology can also be used for the measurement of rats body composition and rats in vivo.

The rats body composition analyzer can quickly, accurately and quantitatively measure the fat, lean meat and body fluid content of rats when the small animal is awake and unrestrained, without anesthesia. Without any harm, it simplifies the experiment, saves the experimental cost, and carries out the follow-up study on a single rat or small animal. By monitoring the physiological parameters of rats for a long time, the effects of various drugs, exercise, external factors and nutrition on the physiological indicators of rats were investigated.

Rats body composition analysis technology is mainly used for quantitative analysis of metabolism-related components such as fat, lean meat and body fluids, assisting in the screening of active ingredients in drugs, and the research on the etiology and pathogenic mechanism of metabolic diseases.

Niumag NMR Analyzer Performance Characteristics:

Quick test: the test is simple and fast, and the whole test process is within 1min;

The sample does not need pre treatment: the sample does not need to be anesthetized or killed;

Test results: The test results are fat content and muscle content, which are reliable and true, with high stability and good repeatability;

Applicability: Small animals such as live rats, mice and rabbits can be measured;

Niumag Rats body composition NM21-060H-I